Work

Bilateral Vasoproliferative Tumors in Usher Syndrome

Year: 2025

Type: article

Abstract: Introduction: Vasoproliferative tumors (VPTs) can be associated with retinal dystrophy, but there are few well-documented cases and even fewer linked to Usher syndrome. Most reported cases are unilateral. The purpose of this report was to describe a case of bilateral sequential VPT in the context of MYO7A-related Usher syndrome. Case Report: A 13-year-old female presented with pain in her left eye and no light perception in that eye. She was found to have left eye advanced neovascular glaucoma related to VPT in the context of MYO7A-related Usher syndrome. Intraocular pressure and pain were controlled with external diode cyclodestruction. Almost 3 years later, early asymptomatic VPT was noted in the right eye during follow-up and was treated with laser photocoagulation. Conclusion: Although VPT is typically unilateral, affected patients need careful follow-up for possible bilateral sequential disease. Early treatment avoids blinding complications.

Source: Case Reports in Ophthalmology

DOI: 10.1159/000542415

Authors: Francesco Pichi, Federico Rissotto, Khalid N. Qadha, Scott D. Smith, Arif O. Khan

Institutions: Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Abu Dhabi, Case Western Reserve University, IRCCS Ospedale San Raffaele, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,030