Work

Retroperitoneal haemangioma masquerading as recurrence of well-differentiated neuroendocrine tumour: a cautionary note

Year: 2025

Type: article

Abstract: Gallium 68-DOTATATE positron emission tomography scanning is the cornerstone of nuclear medicine imaging for neuroendocrine tumours. Previous reports have demonstrated the potential for vertebral haemangiomata to mimic neuroendocrine skeletal metastases. We present the case of a 42-year-old man with a history of well-differentiated neuroendocrine tumour of the appendix, identified incidentally following emergency appendicectomy. Postoperative 68Ga-DOTATATE positron emission tomography/computed tomography scanning revealed an intensely gallium-avid retroperitoneal lesion adjacent to the right psoas muscle. Surgical excision of this lesion was recommended following multidisciplinary team discussion. Histological evaluation of the resected lesion revealed an intravascular capillary haemangioma. Haemangiomas can mimic residual or recurrent neuroendocrine tumour based on gallium avidity, and this should be considered in atypical cases.

Source: Annals of The Royal College of Surgeons of England

DOI: 10.1308/rcsann.2025.0009

Authors: AM AbdelDayem, S Navalkissoor, TV Luong, M Caplin, R Mirnezami

Institutions: Cairo University, Royal Free London NHS Foundation Trust

Language: English

Topic: Neuroendocrine Tumor Research Advances

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4408830669

FWCI: 0.623

Cites: 10

Cited by: 1

Related to: 10