Feasibility and Safety of Intratympanic Administration of Sustained‐Exposure Dexamethasone Thermosensitive Gel (OTO‐104) for Prevention of Cisplatin‐Induced Hearing Loss in Children: A Multisite Phase 2 Randomized Clinical Trial
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Source: Pediatric Blood & Cancer
DOI: 10.1002/pbc.31680
Authors: David R. Freyer, Timothy J. D. Ohlsen, Debra Don, Etan Orgel, Robert J. Hayashi, Judith E. Lieu, Jennifer H. Foster, Matthew S. Sitton, James I. Geller, Daniel I. Choo, Arun Rangaswami, Kay W. Chang, Brian Greffe, Kenny Chan, Alice Lee, Eli Grunstein, Allison F. O'Neill, Reza Rahbar, Jeffery J. Anderson
Institutions: University of Southern California, Children's Hospital of Los Angeles, Seattle Children's Hospital, University of Washington, Seattle Children's Research Institute, Washington University in St. Louis, Texas Children's Hospital, Cincinnati Children's Hospital Medical Center, University of California, San Francisco, Lucile Packard Children's Hospital, Stanford University, University of Colorado Denver, Morgan Stanley Children's Hospital, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston Children's Hospital, Otonomy (United States)
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funder: Otonomy
OpenAlex ID: W4408841759