Work

Targeting the complement system in the management of periodontal disease

Year: 2025

Type: article

Abstract: Periodontitis is a chronic inflammatory disease triggered by microbial antigens colonizing the root surface and pocket epithelium. While mechanotherapy aimed at debridement of root surface biofilms remains the primary treatment, adjunctive therapies targeting host immune responses have gained attention in recent years. The complement system, a key component of innate immunity, plays a crucial role in the pathogenesis of periodontal disease by amplifying inflammatory responses and modulating immune cell activity.

Source: International Journal For Multidisciplinary Research

DOI: 10.36948/ijfmr.2025.v07i02.39720

Authors: Aarcha Hariprasad, Arun K V, Anjali R Nath, Maya Peter

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4408844639

FWCI:

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