Highly Wicking Cellulose Microneedles for Rapid Sampling and Transport of Dermal Interstital Fluid
Year: 2024
Type: conference-paper
Abstract: We report the development of highly wicking cellulose microneedles (MNs) for the rapid extraction and transport of dermal interstitial fluid (ISF).The MN array is made using a unique fabrication process, resulting in mechanically robust microneedles with exceptional wicking properties.For proof of concept, the cellulose MN array was integrated with a lateral flow immunochromatographic assay (LFIA) and tested on an artificial skin model, revealing its ability to autonomously extract fluid for subsequent LFIA-based biomarker detection.
DOI: 10.70477/vowd7335
Authors: Elizabeth Wilkirson, Peter Lillehoj
Institution: Rice University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4408849664