Work

Evaluation of the Effect of Body Mass Index and Waist Circumference on Ocular Health Parameters in Children and Adolescents

Year: 2025

Type: article

Abstract: Background/Objectives: Childhood obesity is a significant health concern also capable of impacting ocular health. This study evaluates the effects of childhood obesity on corneal morphology, anterior chamber parameters, intraocular pressure (IOP), and corneal endothelial cell morphology. Understanding these relationships may contribute to early diagnosis and management strategies. Methods: This prospective, cross-sectional study was conducted at the Harran University Faculty of Medicine between January and December, 2024. Ninety children aged 7–17 years were included, with only the right eyes being analyzed. The participants were categorized into three groups based on body mass index (BMI) percentiles: normal weight (≤85th percentile), overweight (86–94th percentiles), and obese (≥95th percentile). All participants underwent comprehensive ophthalmological examinations, including IOP measurement with a non-contact tonometer, corneal topography assessment using a Scheimpflug camera, and endothelial cell morphology evaluation via specular microscopy. Results: IOP was significantly higher in the overweight and obese groups (p < 0.001). Central corneal thickness (CCT) also increased significantly in these groups (p < 0.05). Positive correlations were determined between BMI and IOP (r = 0.493, p < 0.001) and CCT (r = 0.345, p < 0.001). Additionally, waist circumference exhibited a strong correlation with BMI (r = 0.905, p < 0.001) and a significant association with IOP (r = 0.463, p < 0.001). No significant differences were observed among the groups in terms of other anterior chamber or endothelial parameters. Conclusions: Childhood obesity is associated with increased IOP and CCT, suggesting potential alterations in corneal biomechanics and ocular physiology. These findings highlight the importance of routine ophthalmological evaluation in obese children to detect early ocular changes and prevent long-term complications.

Source: Children

DOI: 10.3390/children12040413

Authors: İrfan Uzun, Enes Colak, Zeliha Atlıhan, Çağrı Mutaf, Ali Hakim Reyhan, Funda Yüksekyayla

Institution: Harran University

Language: English

Topic: Corneal surgery and disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896