Work

Unusual presentation of cowper gland adenocarcinoma Mimicking post-traumatic urethral stricture

Year: 2025

Type: article

Abstract: Urethral strictures are commonly attributed to trauma, inflammation, or iatrogenic causes, but malignancies are a rare etiology. We report a case of a 57-year-old male with a history of trauma presenting with a bulbomembranous urethral stricture, initially suspected as post-traumatic. Intraoperative frozen section analysis unexpectedly revealed Cowper gland adenocarcinoma, leading to definitive surgical management with radical cystoprostatectomy and urethrectomy. This case underscores the importance of considering malignancy in atypical stricture presentations to ensure accurate diagnosis and appropriate treatment. • Cowper gland adenocarcinoma is a rare but critical differential in urethral strictures. • Malignancy should be considered in atypical urethral stricture presentations. • Intraoperative frozen section analysis aided in the unexpected urethral cancer diagnosis. • Radical cystoprostatectomy and urethrectomy were necessary for definitive treatment. •Early recognition of Cowper malignancy can prevent delays in appropriate management.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103027

Authors: Babak K. Azad, Hung L. Do, Joel Gelman

Institutions: Tulane University, Bệnh viện Bình Dân, University of California, Irvine

Language: English

Topic: Urinary and Genital Oncology Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160