Mixed mullerian tumour presenting as giant uterine mass: a case report and review of literature
Year: 2025
Type: article
Study design: Case Report
Abstract: Malignant mixed Müllerian tumors (MMMT) of the uterine corpus, also referred to as uterine carcinosarcomas, are rare and aggressive neoplasms, accounting for only 1–2% of uterine cancers. These tumors exhibit poor prognosis, with a 5-year survival rate of approximately 30% and only 50% being diagnosed at an early stage. Early detection is crucial, and imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) play a critical role in assessing tumor size, metastasis, and infiltration. The standard treatment involves surgical resection combined with platinum-based chemotherapy. Here, we present a rare case of a giant uterine mass in a 67-year-old female, confirmed to be MMMT. The patient underwent surgical debulking followed by chemotherapy, achieving significant resolution as evidenced by imaging. This case highlights the importance of early diagnosis and multimodal treatment in improving outcomes in MMMT.
Source: International Surgery Journal
Authors: Vrushabh R. Doshi, Vijay R. Naik, Bossuet Afonso, Aparna Joshi, Chitralekha A. Nayak
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408857170