Work

Gastrointestinal stromal tumor causing bleeding and intussusception: A case report

Year: 2025

Type: article

Abstract: INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that originate from interstitial cells of Cajal. They most commonly occur in the stomach, followed by the small bowel. Jejunal GISTs are particularly rare and often present with nonspecific symptoms. However, they can also present with gastrointestinal bleeding and intussusception, complicating diagnosis and treatment. PRESENTATION OF CASE: We report a case of a 58-year-old male who presented with melena and anemia due to a bleeding intussuscepting jejunal gastrointestinal stromal tumor (GIST). The patient underwent jejunal resection and anastomosis. The postoperative course was uncomplicated, and the patient made a full recovery. DISCUSSION: Gastrointestinal stromal tumors (GISTs) can present with melena and acute or chronic anemia due to gastrointestinal bleeding. The bleeding typically results from ulceration or erosion of blood vessels within the tumor. The diagnosis is often challenging, as the symptoms are nonspecific. Imaging techniques such as CT scans are essential for identifying the tumor, and surgical resection is the primary treatment, providing favorable outcomes for localized, low-risk cases. CONCLUSION: Gastrointestinal stromal tumors (GISTs), although rare, should be considered in the differential diagnosis of patients presenting with gastrointestinal bleeding and anemia.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.111203

Authors: Abanoub Awad, Isaac Theerman, Jason Beckermann

Institution: Mayo Clinic Health System

Language: English

Topic: Gastrointestinal Tumor Research and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090