Work

Acquired partial lipodystrophy (Barraquer-Simons syndrome) with both-side axillary breasts: A case report

Year: 2025

Type: article

Abstract: INTRODUCTION: Lipodystrophies are conditions characterized by a loss of subcutaneous fat, which can be congenital or acquired, and present in various patterns of fat distribution. Accurate diagnosis is essential for identifying comorbidities and ensuring appropriate multidisciplinary care and targeted treatments. CASE PRESENTATION: A 34-year-old female experienced significant facial changes and increased abdominal fat over five years. She had lumps under her armpits discharging white fluid, with clinical findings of low hemoglobin and accessory breast tissue, which was surgically excised. DISCUSSION: Acquired generalized lipodystrophy is often overlooked, with over 250 documented cases. It typically presents in adolescence and involves symmetrical fat loss, with potential associations to autoimmune diseases and unique features in this case. CONCLUSION: This case emphasizes the complexities of acquired lipodystrophy, especially regarding accessory breast tissue. It highlights the need for thorough evaluations and increased awareness among healthcare providers for timely diagnosis and management.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.111202

Authors: Mohammad Al-Jawad, Lina Mawaldi, Nada Mawaldi, Mariam Krimsty, Silva Ishkanian

Institution: University of Aleppo

Language: English

Topic: Lipid metabolism and disorders

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090