Work

Mechanism of Formation of “guest-host” Complexes Between Rutin and 2-hydroxypropyl-beta-cyclodextrin

Year: 2025

Type: article

Abstract: ATR-FTIR and NMR spectroscopy were used to investigate the mechanism of plant antioxidants’ interactions with 2-hydroxypropyl-beta-cyclodextrin, using rutin as an example. Rutin is characterized by the aromatic skeleton’s incorporation into the cyclodextrin torus and stabilization brought about by the interaction between the cyclodextrin’s –OH groups and the carbohydrate moiety.

Source: Lomonosov chemistry journal

DOI: 10.55959/msu0579-9384-2-2025-66-1-67-71

Authors: Irina Le-Deygen, Thi Lan Pham, Anna Skuredina, Pavel Markov, Van Cuong Bui, Thi My Hanh Le, Hoang Trang Nguyen, Tatyana Savitskaya

Institutions: Lomonosov Moscow State University, Institute for Tropical Technology, Vietnam Academy of Science and Technology, VNU University of Education, Belarusian State University

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4408871690

FWCI: 0.337

Cites: 9

Cited by: 1

Related to: 10