Work

Network analysis of splenic gene expression of cattle co-infected with bovine viral diarrhea virus 2 and bovine herpes virus 1 following vaccination and trace mineral administration

Year: 2025

Type: conference-abstract

Abstract: A common management practice to prevent bovine respiratory disease (BRD) in dairy and beef cattle often involves the administration of modified-live virus (MLV) vaccines. In addition, injectable trace minerals (ITM) concomitant with vaccination has been associated with an improved immune response and protection elicited by vaccine antigens. While widely utilized, the influence these tools have on immunomodulation and cellular mobilization within central lymphoid tissue is largely unknown. To our knowledge, this study is the first to comprehensively evaluate gene expression patterns from cattle administered MLV vaccines and ITM followed by BVDV2 and BHV1 challenge.

Source: American Association of Bovine Practitioners Conference Proceedings

DOI: 10.21423/aabppro20249165

Authors: M.A. Scott, R.A. Palomares, M.K. Linson, E.G. Altamiranda, A. Hoyos-Jaramillo, J.H. Bittar, A. Rodriguez, J. Urdaneta

Institutions: Texas A&M University, University of Georgia, West Texas A&M University, Consejo Nacional de Investigaciones Científicas y Técnicas, National Agricultural Technology Institute, University of Florida

Language: English

Topic: Animal Virus Infections Studies

Subfield: Animal Science and Zoology

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Zero hunger, Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408882948

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