Work

Describing biosynthetic gene clusters of dairy cattle uterine microbiomes associated with antimetritis properties

Year: 2025

Type: conference-paper

Abstract: Uterine disease perturbs fertility thereby causing economic losses to the dairy enterprise worldwide. About 25-40% of dairy cattle develop metritis postpartum (Sheldon et al., 2009). 16S rRNA amplicon sequencing taxonomic identification of the endometrial microbiome signatures differentiate cattle harboring uterine disease (Becker et al., 2023), particularly at 7 and 10 days postpartum (DPP), before clinical signs of metritis are evident (Tasara et al., 2023). It is hypothesized that predominating bacterial strains inhabiting the healthy bovine uterus postpartum elucidate antimicrobial molecules that hinder pathogens causing endometritis. This study aims to describe predictive biosynthetic gene clusters (BGCs) present in the healthy bovine endometrial microbiome that may be protective against metritis.

Source: American Association of Bovine Practitioners Conference Proceedings

DOI: 10.21423/aabppro20249183

Authors: P. Fayek, R.C. Whiston, C.G. Moreno, M. Biggel, T. Tasara, U.T. Bleul, A. Chapwanya

Institutions: Ross University School of Veterinary Medicine, National University of Tucumán, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto Superior de Investigaciones Biológicas, University of Zurich

Language: English

Topic: Reproductive Physiology in Livestock

Subfield: Agronomy and Crop Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W4408882995

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