Work

[Effects of cell area on single odontoblast polarization and differentiation via microarray technology].

Year: 2025

Type: other

Abstract: OBJECTIVES: This study aimed to explore the impact of cell spreading area on odontoblast polarization and differentiation using micropatterned surfaces ge-nerated by photolithography. METHODS: . Immunofluorescence staining was used to observe cell morphology and analyze the relocating of the golgi apparatus and nucleus. Alkaline phosphatase staining was preformed to examine odontogenic differentiation. RESULTS: <0.05). CONCLUSIONS: The polarization and differentiation of single hDPSCs increased with the cell areas on micropatterned surfaces.

Source: PubMed

DOI: 10.7518/hxkq.2025.2024392

Authors: Huen Li, Nianzuo Yu, Xiheng Li, Xiaoduo Tang, Yalu Sun, Chao Si, Junhu Zhang, Bei Chang

Institutions: Jilin University, First Hospital of Jilin University, State Key Laboratory of Supramolecular Structure and Materials

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W4408884622

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