Delivering on the Promise of Precision Oncology in Prostate Cancer: Prediagnostic Strategies, Postdiagnostic Applications, and Future Directions. A Narrative Review
Year: 2025
Type: review
Abstract: Precision oncology offers a transformative approach to managing localized prostate cancer (PCa) by tailoring interventions to the biological characteristics of the disease. This strategy addresses critical challenges such as overdiagnosis, overtreatment, and the underutilization of advanced diagnostics. Despite the advancements, barriers such as tumor heterogeneity, patient variability, high costs, and limited accessibility impede widespread adoption of new technologies and risk assessment tools. Looking ahead, innovations in biomarker discovery, artificial intelligence, and machine learning hold promise for further refining risk prediction, treatment selection, and active surveillance protocols. By addressing these challenges and advancing precision tools, precision oncology can transform the management of localized PCa, enabling personalized care that minimizes overtreatment while ensuring optimal outcomes.
Source: Journal of Urologic Oncology
Institution: Yale University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408887616