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Neuronal receptors at body temperature reveal their gating mechanics

Year: 2025

Type: article

Abstract: Most communication between neurons is mediated by the neurotransmitter glutamate. The finding that temperature influences how glutamate binds to neuronal receptor proteins to initiate signal transduction reveals the mechanics of one of the brain’s most important processes. Structures of drug-free brain receptors are resolved by warming them to physiological temperatures.

Source: Nature

DOI: 10.1038/d41586-025-00865-y

Language: English

Topic: Neuroscience and Neuropharmacology Research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4408888164

FWCI:

Cites: 5

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Related to: 10