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Prevalence of CMV glycoprotein B genotypes in newborns with congenital CMV infection in Southern Bahia, Brazil

Year: 2025

Type: article

Abstract: Cytomegalovirus (CMV) is a common herpesvirus that causes congenital infections with significant neonatal health risks. This study characterized CMV glycoprotein B (gB) genotypes among 2,595 newborns in Southern Bahia, Brazil. CMV DNA was detected in 1.19% of cases, with gB1, gB2, and gB3 identified among the infected infants (gB2 and gB1 being the most prevalent). Although follow-up evaluations showed no statistically significant correlation between genotypes and late sequelae, three infants exhibited hearing loss. These findings highlight the predominance of gB1 and gB2 in the studied region, emphasizing the need for targeted prevention and management strategies.

Source: Brazilian Journal of Development

DOI: 10.34117/bjdv11n3-050

Authors: Lauro Juliano Marin, Felipe Charu Ramos, Pérola Rodrigues dos Santos, Uener Ribeiro dos Santos, Marcus Vinícius Menezes, Luciana Debortoli de Carvalho, Sandra Rocha Gadelha, Victor Hugo Aquino

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408890276

FWCI:

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