Work

The relationship between major anomalies and chorionicity in twin pregnancies referred for first trimester and second trimester detailed anatomic ultrasonography

Year: 2025

Type: article

Abstract: OBJECTIVES: The purpose of this study is to validate the relationship between chorionicity and congenital anomalies. MATERIAL AND METHODS: A retrospective analysis twin pregnancies that underwent ultrasonographic fetal anatomy screening in the first or second trimester was conducted. Analyzed variables were, gestational age, chorionicity, presence of major fetal structural anomalies, number of affected fetuses, anomaly type, and use of assisted reproductive techniques (ART). RESULTS: Of the 824 twin pregnancies included in the study, 116 (14%) had major fetal anomalies. The frequency of major fetal structural anomalies was higher in monochorionic (MC) twin pregnancies compared to dichorionic (DC) twin pregnancies (p < 0.001). When anomalies were categorized into cardiac, central nervous system, and other system anomalies, no significant correlation was found between chorionicity and anomaly groups (p = 0.794). CONCLUSIONS: In MC twin pregnancies, major fetal structural abnormalities are more prevalent. Prioritizing the evaluation of chorionicity is essential due to the increased risk associated with twin pregnancies.

Source: Ginekologia Polska

DOI: 10.5603/gpl.102670

Authors: Ercan Koçkaya, Yasemin Doğan, Abdulkadir Babaoğlu

Institutions: Ministry of Health, Kocaeli Üniversitesi

Language: English

Topic: Assisted Reproductive Technology and Twin Pregnancy

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $431