Work

Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report

Year: 2025

Type: article

Abstract: OBJECTIVE: Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate. METHODS: We report a 16-year-old girl diagnosed with nortriptyline poisoning with a profound neurologic and cardiovascular manifestations, successfully treated using sodium bicarbonate, intralipid emulsion, and plasmapheresis. CONCLUSIONS: Plasmapheresis can be a good treatment modality for patients with TCA poisoning who do not respond well to classic treatments.

Source: International Journal of Emergency Medicine

DOI: 10.1186/s12245-025-00824-4

Authors: Asma Ahmadinejad, Amir Saeed, Marzieh Davoodi

Institutions: Shiraz University, Shiraz University of Medical Sciences

Language: English

Topic: Poisoning and overdose treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090