Investigating the Antimicrobial Potential of Plant-Based Protein Against Human Pathogens
Year: 2025
Type: article
Abstract: The growing incidence of antibiotic-resistant pathogens requires the investigation of alternative antimicrobial compounds, especially plant-based proteins (PBPs). This review explores the antimicrobial capability of PBPs against human pathogens, emphasizing their effectiveness against multidrug-resistant organisms. Several studies indicate that plant-derived compounds with important oils and proteins display antibacterial and antifungal properties. Key instructions of PBPs, including lectins, defensins, and protease inhibitors, disrupt microbial membranes and inhibit vital cell features, lowering pathogen viability. The mechanisms of movement of these proteins are numerous, which might also decrease the likelihood of resistance development compared to artificial antibiotics. The potential of plant-derived antimicrobial peptides (AMPs) to successfully kill bacteria at low doses with little resistance makes them interesting. This overview highlights the efficacy of positive plant extracts, particularly those from Moringa oleifera and Myrtus communis, against infections such as Staphylococcus aureus and Listeria monocytogenes. PBPs can be used in food safety and to treat continual infection. This study emphasizes the significance of using natural assets to address antibiotic resistance by refining extraction techniques and examining bioactive substances. To improve public fitness strategies against resistant infections and examine their functional roles in current medication, further research is required on the mechanisms and implementation of PBPs.
Source: Premier journal of science.
DOI: 10.70389/pjs.100070
Authors: Saira Sameen, M. Bilal Khalil, M. Usama Khalil
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4408910761