Phenotypic Classification and Polysomnographic Patterns in Pediatric Obstructive Sleep Apnea
Year: 2025
Type: article
Abstract: Pediatric obstructive sleep apnea (OSA) presents unique challenges in diagnosis and management, particularly when considering the diverse phenotypes that can be observed by polysomnography (PSG). Phenotypes of pediatric OSA can be broadly categorized into common, adult and congenital phenotypes, each associated with distinct anatomical and physiological characteristics that influence both the presentation and treatment outcomes of OSA. The common phenotype typically involves tonsillar and adenoidal hypertrophy, which is prevalent in early childhood and can lead to significant airway obstruction. The congenital phenotype is often associated with syndromes such as Pierre Robin sequence or Down syndrome, which involves structural abnormalities that severely compromise airway patency. The adult phenotype in children, often associated with obesity, exhibits symptoms similar to those seen in adult patients with OSA. This review explores current research to highlight the importance of phenotype-specific diagnostic and treatment strategies to improve treatment efficacy and patient outcomes. Through a detailed analysis of various studies, this paper highlights the need for accurate phenotype identification using PSG to effectively tailor interventions and improve the overall management of pediatric OSA.
Authors: Sookyoung Park, Chan-Soon Park
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408911920