Work

Early postpartum calcium dysregulation is associated with acute phase responses in multiparous Holsteins

Year: 2025

Type: conference-paper

Abstract: During the transition into lactation, multiparous Holstein cows commonly experience calcium dysregulation at 4 DIM. This condition, also known as dyscalcemia, has been associated with increased risk of disease, decreased intake and production, and poor reproductive performance. It is also common for early lactation cows to experience systemic inflammation immediately following parturition. More sustained or severe bouts of postpartum inflammation have been associated with suboptimal outcomes, similar to those experienced by dyscalcemic cows. The acute phase response, an important inflammatory process mediated by the liver, can serve as a marker for systemic inflammation, therefore the objective of this study was to explore differences in the acute phase response between cows with and without dyscalcemia. We hypothesized that cows with dyscalcemia would experience more extreme acute phase responses than eucalcemic cows.

Source: American Association of Bovine Practitioners Conference Proceedings

DOI: 10.21423/aabppro20249142

Authors: J.A. Seminara, C.R. Seely, J.A.A. McArt

Institutions: Cornell University, New York State College of Veterinary Medicine

Language: English

Topic: Reproductive Physiology in Livestock

Subfield: Agronomy and Crop Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W4408912164

FWCI:

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