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Synthesis of indole-linked β-cyano-enones: a pathway to indolyl-2-pyrrolones

Year: 2025

Type: article

Abstract: The multicomponent reaction of arylglyoxal, malononitrile, and indoles in DMF yields indole-linked β-cyano-enones, which serve as precursors for medicinally relevant 2-pyrrolones, 1,2-diketones, and quinoxalines.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/d5ob00328h

Authors: Nurabul Mondal, Vidya Kumari, Danish Ali, Lokman H. Choudhury

Institution: Indian Institute of Technology Patna

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Science and Engineering Research Board

Award: G3966269295

OpenAlex ID: W4408912256

FWCI: 0.894

Cites: 29

Cited by: 3

Related to: 10