Radiation-Induced Leomyosacroma of the Larynx: A Case Report and Literature Review
Year: 2025
Type: article
Study design: Case Report
Abstract: There is a clear association between radiotherapy and an increased risk of developing secondary cancers, including sarcomas. Leiomyosarcoma is one of the rare secondary tumors reported after radiotherapy treatment. We report a rare case of laryngeal leiomyosarcoma in a 72-year-old patient with a history of radiotherapy for nasopharyngeal carcinoma treated seventeen years earlier. The patient mainly presented with progressively worsening dysphagia. The treatment consisted of surgical excision followed by adjuvant radiotherapy. The outcome was favorable. Through this case report, we aim to highlight this rare secondary tumor and its association with the effects of radiotherapy. We will also review the main therapeutic modalities for this entity.
Authors: Salma El Alaoui El Rhoul, Hajar El Youbi, Abdellatif Oudidi, Nawal Hamass, Najib Benmansour, Naouar Ouattassi, Mohammed Ridal, Mohammed Noureddine El Amine El Alami
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408915955