Chemotherapy-Induced Neutropenic Enterocolitis in Acute Myeloid Leukaemia Patient: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: This case report details a 53-year-old woman with newly diagnosed acute myelogenous leukaemia (AML) who developed neutropenic enterocolitis (typhlitis) following induction chemotherapy. Initially presenting with mild respiratory symptoms and blood abnormalities, her condition worsened after chemotherapy, leading to severe gastrointestinal issues and pancytopenia. Diagnostic imaging and blood cultures confirmed neutropenic enterocolitis caused by Escherichia coli. The patient was successfully treated with broad-spectrum antibiotics, G-CSF, blood transfusions, and supportive care, resulting in a full recovery. This case highlights the importance of early diagnosis and prompt treatment of neutropenic enterocolitis in AML patients undergoing chemotherapy to improve outcomes and reduce mortality.
Authors: Vijay Yaswanth Reddy Bade, Gunasekaran Nallusamy, Manju, K, Subbiah Senthil Nathan, Boojhana Elango, Pavithra R, Maghimaa, M
Institution: Saveetha University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4408918628