Work

Carbon-Infiltrated Carbon Nanotube Topography Reduces the Growth of Staphylococcus aureus Biofilms

Year: 2025

Type: article

Abstract: Orthopedic implant-associated infections are a growing problem. These infections are often associated with bacterial biofilms, such as those formed by Staphylococcus aureus. Nanotextured surfaces can reduce or prevent the development of bacterial biofilms and could help reduce infection rates and severity. Previous work has shown that a carbon-infiltrated carbon nanotube (CICNT) surface reduces the growth of S. aureus biofilms. This work expands on previous experiments, showing that the topography of the CICNT, rather than its surface chemistry, is responsible for the reduction in biofilm growth. Additionally, the CICNT surface does not reduce biofilm growth by killing the bacteria or by preventing their attachment. Rather it likely slows cell growth, resulting in fewer cells and reduced biofilm formation.

Source: Nanomaterials

DOI: 10.3390/nano15070510

Authors: Lucy C. Bowden, Sidney T. Sithole, Anton E. Bowden, Brian D. Jensen, Bradford K. Berges

Institution: Brigham Young University

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896