Work

[18F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana

Year: 2025

Type: article

Abstract: F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing multiple FDG-avid osteolytic lesions of the axial skeleton including a vertebra plana of T7 and paraosseous soft tissue lesions. A CT-guided biopsy confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case highlights the importance of considering LCH in young patients with vertebral collapse and underscores the role of PET/CT imaging in establishing an accurate diagnosis.

Source: Diagnostics

DOI: 10.3390/diagnostics15070862

Authors: Tilman Speicher, Moritz B. Bastian, Konstantinos Christofyllakis, Florian Rosar, Samer Ezziddin, Caroline Burgard

Institution: Saarland University

Language: English

Topic: Histiocytic Disorders and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137