Work

Suppression of BRCA1 facilitates kidney regeneration

Year: 2024

Type: article

Abstract: Maladaptive repair following kidney injury leads to the development of kidney disease. In this issue of JEM, Ajay et al. (https://doi.org/10.1084/jem.20231107) uncover the role of breast cancer susceptibility gene 1 (BRCA1) in cell cycle arrest, DNA damage, and cell senescence, preventing maladaptive repair.

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20241814

Authors: Kaira A. Church, Xunian Zhou, Raghu Kalluri

Institutions: The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, Rice University

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4408939741

FWCI: 0.247

Cites: 12

Cited by: 1

Related to: 10