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Ethanolic Extract of Terminalia catappa Kernel: A Natural Remedy with Promising Pharmacological Potential

Year: 2025
Type: article
Abstract: A relationship between humans and nature began with our ancestral reliance on natural resources for survival and health. This relationship has profoundly influenced the field of pharmacology through the discovery and utilization of natural product drugs, demonstrating the enduring importance of nature in medicine and the ongoing exploration of its therapeutic potential. This study investigates the pharmacological potential of the ethanolic extract of Ceylon almond kernel (Terminalia catappa), highlighting its antioxidant (IC50 = 21.68 ± 1.97 µg/mL), anti-inflammatory (IC50 = 180.14 ± 3.99 µg/mL) and α-amylase inhibitory (IC50 = 147.77 ± 4.74 µg/mL) activities. It also showed antibacterial activity against various pathogens and minimal UV protection (SPF = 5.27 ± 0.63). These results suggest that the Ceylon almond kernel could be a promising natural source for pharmaceutical applications and drug development.
Authors: H.A.L.D. Jayawardhana, D.H.D. DewageDona, C.S.K. Rajapakse
Language: English
Subfield: Plant Science
Open Access status: diamond
OpenAlex ID: W4408955759
FWCI:
Cites: 39
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Related to: 10