Work

Successful use of pulsatile flow and goal directed perfusion in a high-risk patient

Year: 2025

Type: article

Abstract: The development of multi-organ failure resulting from cardiopulmonary bypass (CPB) is acknowledged as a significant contributor to increased morbidity and mortality rates during the postoperative period. This report discusses a patient who presents with multiple comorbidities, including renal failure, reduced ejection fraction, and a history of hypertension, and is being considered for coronary artery bypass grafting (CABG) along with aortic valve replacement surgery. The administration of CPB was customized to address the unique comorbid conditions of the patient, highlighting the critical objective of maintaining an oxygen delivery index (DO2i) exceeding 280 mL/min/m2, while also integrating pulsatile flow methodologies. The management of CPB, as previously discussed, resulted in a notable enhancement of kidney function, accompanied by a reduction in the patient’s lactate levels post-surgery.

Source: Journal of ExtraCorporeal Technology

DOI: 10.1051/ject/2025002

Authors: Mostafa Bagherinasab, Nathaniel H. Darban

Institutions: Baqiyatallah University of Medical Sciences, Midwestern University

Language: English

Topic: Cardiac and Coronary Surgery Techniques

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,300