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Reproductive factors as a risk factor for STEMI: A retrospective case-control study

Year: 2025

Type: article

Abstract: This study explored connections between women's reproductive factors and acute ST-segment elevation myocardial infarction (STEMI). A retrospective case-control study was conducted between 2016 and 2017. The study included 110 women diagnosed with STEMI and 110 control participants. Data on reproductive factors were collected through structured questionnaires and analyzed using statistical methods. Findings showed that increased STEMI risk was associated with longer lactation period, a higher number of parities, gravidity, and abortions. No significant relationships were observed for menopausal status, menopausal age, menarche age, reproductive duration, or oral contraceptive use. This study revealed that higher gravidity, parity, history of abortion, and longer breastfeeding duration were linked to an increased risk of STEMI. However, no significant differences were found between the case and control groups regarding menopausal status, age at menopause, age at menarche, reproductive duration, or oral contraceptive use.

Source: Medicine

DOI: 10.1097/md.0000000000041974

Authors: Azam Soleimani, Fatemeh Sadat Khademi, Zahra Soleimani, Mohammad Hossein Paknahad, Hamidreza Roohafza, Masoumeh Sadeghi

Institutions: Isfahan University of Medical Sciences, Baqiyatallah University of Medical Sciences, Abadan University of Medical Sciences

Language: English

Topic: Acute Myocardial Infarction Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950