Work

Oscillometry and spirometry derived ratios to assess small airways dysfunction in severe asthma patients taking tezepelumab

Year: 2025

Type: article

Abstract: Forced oscillometry technique is an effort independent test that imposes varying frequency soundwaves onto normal tidal breathing. This allows the measurement of the pressure/flow relationship of respiratory impedance and thus the calculation of resistance (R) and reactance components (X). Resistance at 5Hz (R5) represents lung resistance throughout the entire airways, whereas resistance at 20Hz (R20) is representative of the larger airways. Thus the heterogeneity between R5 and R20 represents the resistance in peripheral airways.

Source: Respiratory Medicine

DOI: 10.1016/j.rmed.2025.108072

Authors: Robert Greig, Rory Chan, Brian Lipworth

Institution: University of Dundee

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,630