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Bone Marrow Aspirate – A Diagnostic Tool in Hematology, Importance, and Applications: Experience from Jordanian Royal Medical Services

Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: A bone marrow aspirate is a medical procedure used to extract a small amount of bone marrow fluid and cells for examination under microscope. It is a very useful diagnostic tool in hematological field. It provides information on bone marrow cells’ function and morphology in different hematological conditions. OBJECTIVES: This study objective is to spot the role of bone marrow aspirate in the diagnosis of different hematological disorders, highlighting its importance and applications. MATERIALS AND METHODS: We reviewed and analyzed 600 bone marrow aspirate from 2022 to 2024 depending on the morphology as the base of this study along with flowcytometry, cytogenetic, and molecular study. RESULTS: We analyzed 600 bone marrow samples from patients aged 1 month to 85 years, with a male-to-female ratio of 1.5:1. Among findings, 62.2% had hematological diseases (malignant: 39.4%, benign: 22.8%), 2.99% had nonhematological conditions, 3.79% were inadequate, and 34.36% showed normal findings. CONCLUSION: Bone marrow aspirate examination plays a significant role in identifying and diagnosing different hematological diseases.
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4408979244
FWCI:
Cites: 12
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Related to: 10