Work

Granulomatous mastitis - Case report

Year: 2025

Type: article

Abstract: INTRODUCTION AND IMPORTANCE: Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory breast disease with unclear etiology and no standardized treatment. It often presents as a painful breast mass that mimics breast cancer, necessitating thorough diagnostic evaluation. CASE PRESENTATION: This report discusses a case of a 39-year-old pregnant woman with IGM associated with erythema nodosum, a poorly understood co-occurrence. Initial treatment included antibiotics and surgical drainage for an abscess. Despite multiple interventions, including corticosteroids and methotrexate, the disease persisted with recurrent episodes. CLINICAL DISCUSSION: This case underscores the complexities of managing IGM, highlighting its association with systemic manifestations such as erythema nodosum. Current therapeutic approaches range from conservative management to immunosuppressive therapy and surgery, with outcomes varying widely. CONCLUSION: Further studies are needed to elucidate the pathophysiology and establish optimal treatment strategies for IGM, particularly in the context of systemic involvement.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.111222

Authors: Catarina Gil Ribeiro, Alice Pimentel, Rita Lages, Ana Isabel Ferreira, João Barros da Silva

Institution: Unidade Local de Saúde do Tâmega e Sousa

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090