Work

Catheter-based Ventricular Assist Device-induced Severe Hyperthermia

Year: 2025

Type: article

Abstract: BACKGROUND: Hemolysis is a potential complication of catheter-based ventricular assist devices (CVADs), but severe hyperthermia is a rare occurrence that significantly affects further management and outcomes. CASE SUMMARY: A young man with toxic methamphetamine-associated cardiomyopathy presented with cardiogenic shock, prompting placement of a CVAD. He soon developed severe hyperthermia unresponsive to cooling measures. The hyperthermia ultimately subsided with removal of the device. DISCUSSION: Hemolysis and renal failure are known complications of CVAD placement. The hyperthermia in this patient was likely related to erythrocytosis, highly viscous blood, and resulting hemolysis. The patient returned to normothermia only after removal of the device, supporting the idea that the CVAD was a cause of hyperthermic episode. TAKE-HOME MESSAGES: The use of CVADs in cardiogenic shock offers favorable outcomes but has potential complications. This unique case of severe hyperthermia resulting from massive hemolysis that required prompt removal of the device supports a rare, high-morbidity potential complication.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2026.110201

Authors: Sarah Noorani, Tyson Burnham, Eric Zuniga, Antonio H. Frangieh, Andy Y. Lee

Institutions: University of California, Irvine Medical Center, Hoag Memorial Hospital Presbyterian, University of California, Irvine

Language: English

Topic: Mechanical Circulatory Support Devices

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850