Work

Assessing Correlations Between Radiographic Classification and Patient-Reported Outcome Measures for Symptomatic Thumb Carpometacarpal Osteoarthritis

Year: 2025

Type: article

Abstract: Purpose: Clinicians routinely use the Eaton-Glickel radiographic classification to stage severity of thumb carpometacarpal osteoarthritis (CMC OA). Our purpose was to evaluate correlations between baseline radiographic stages and prospectively collected patient-reported outcome measures (PROMs) for CMC OA. Methods: This is a retrospective review of prospectively collected data from a larger observational study of patients aged 35-85 years with newly symptomatic thumb CMC OA. Patients with bilateral presentation complete PROMs for each side. We identified patients with adequate radiographs available for review and who had completed baseline PROMs. PROMs were collected electronically and included the Brief Michigan Hand Questionnaire and visual analog/numerical rating scales regarding pain as well as Patient-Reported Outcomes Measurement Information System Pain Interference v1.1 and Global Health modules. We recorded participants' demographics, medical and surgical history, prior treatments, and PROM scores at initial presentation. A medical student was first taught by a fellowship-trained hand surgeon on Eaton-Glickel radiographic staging. They each then independently staged the first 40 series of radiographs. After establishing adequate reliability, the student staged the remaining available radiographic series. We used Cohen's Kappa analyses to determine intrarater reliability and interrater reliability. We used Spearman's rho to assess correlations between PROM scores and radiographic stages. Results: < .05). We found no significant correlations between any PROMs and radiographic staging. Conclusions: Our study adds to growing evidence that radiographic severity for thumb CMC OA does not correlate with validated PROMs. It is becoming clearer that objective measures of CMC OA severity do not fully capture the way patients experience this condition. Type of study/level of evidence: Therapeutic IV.

Source: Journal of Hand Surgery Global Online

DOI: 10.1016/j.jhsg.2025.01.011

Authors: Bradley Nelson, Roland Zama, Kavya K. Sanghavi, Aviram M. Giladi, Kenneth R. Means

Institutions: Georgetown University, MedStar Union Memorial Hospital, MedStar Health Research Institute

Language: English

Topic: Orthopedic Surgery and Rehabilitation

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500