Work

Chondroid lipoma of soft tissue: immunohistochemical study

Year: 2025

Type: article

Abstract: This article presents a clinical case of a rare soft tissue tumor, chondroid lipoma of the right leg, characterized by a complex morphological structure with myxoid areas, lipoblast-like cells, and zones of ossification. Despite histological similarities with chondroblastoma, parosteal osteochondromatous proliferation, myxoid liposarcoma, and chondrosarcoma, immunohistochemical (IHC) analysis and correlation with clinical and instrumental data allowed these pathological processes to be excluded. Chondroid lipoma is a rare benign tumor, and its complex structure and potential for ossification can pose significant challenges in differential diagnosis. This case emphasizes the importance of a comprehensive approach, combining morphological, clinical, and imaging data, for the accurate diagnosis of rare bone and soft tissue tumors.

Source: Health and Ecology Issues

DOI: 10.51523/2708-6011.2025-22-1-17

Authors: V. V. Grishakov, G. V. Tishchenko, V. N. Tishchenko

Institutions: Moscow City Oncology Hospital №62, Gomel State Medical University, Gomel Engineering Institute, Association for Molecular Pathology

Language: English

Topic: Soft tissue tumors and treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4408992404

FWCI:

Cites: 7

Cited by:

Related to: 10