Urea-secreting Function of the Liver and Urea-Secreting Function of the Kidneys after Liver Resection and Hyperbaric Oxygenation
Year: 2025
Type: article
Abstract: hepatica blood was obtained from the interlobular (left and middle lobes of the liver) sinus after its isolation from the posterior vena cava in situ.Operated animals were euthanized under ethaminal anesthesia on the 3 rd day after LR; oxygenated animals -immediately after the end of the third session of HBO.The urea content in the tissue and biological luids was determined by the diacetyl monooxime method [3].The research results were processed statistically using the parametric Student t -test and the nonparametric Mann-Whitney test after preliminary veri ication of the hypothesis of the normality of the sample distribution.The results were considered signi icant at a p value of < 0.05.Statistical analysis was performed using the packages "Microsoft Excel", Statistica 5.0 (StatSoft) " and "Biostat". ResultsNormally, the urea content in the blood from the v. hepatica signi icantly exceeded that in arterial blood and v. porta blood, which made the hepatic arterio-venous (hAVDu) and porto-venous (PVDu) differences in urea negative (Table 1).This indicates the incretion of urea from the intact liver into the central bloodstream.Arterio-portal (APDu) and renal arterio-venous (rAVDu) differences in urea were positive (Table 1).This indicates the excretion of "arterial" urea into the lumen of the gastrointestinal tract and renal tubules, respectively.The concentrations of urea in LLL and MLL did not signi icantly differ (Table 1).On the 3 rd day after LR, the urea content in LLL, bile, and arterial blood did
Source: Journal of Clinical Nephrology
Authors: Pavel Savilov, DV Molchanov
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408994569