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NOACS in the Chronic Renal, Hepatic and Obstructive Pulmonary Diseases

Year: 2025

Type: article

Abstract: Non-vitamin K antagonist oral anticoagulants (NOACs) are used worldwide for the management of thrombotic episodes in patients with atrial fibrillation (AF) or venous thromboembolism (VTE). Patients with chronic kidney disease (CKD), chronic liver insufficiency (CLI), and chronic obstructive pulmonary disease (COPD) are prone to develop AF and VTE in the long term. Specifically, both diseases, CKD and CLI are at increased risk of developing thrombotic and bleeding episodes. This leads to cautious dosing of each NOAC to target the thrombotic risk and prevent the bleeding risk. This manuscript will help physicians understand the dose regimen for prescribing NOACs in the above-mentioned chronic conditions.

Source: Pakistan Heart Journal

DOI: 10.47144/phj.v58i1.2725

Authors: Syed Haseeb Raza Naqvi, Han Naung Tun, F. Aaysha Cader, Jolanda Sabatino, Madiha Fatima

Institutions: Ch. Pervaiz Elahi Institute of Cardiology, Multan, University of Vermont, University of Vermont Medical Center, Ibrahim Cardiac Hospital & Research Institute, University of Padua, National Institute of Cardiovascular Diseases

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408994727

FWCI:

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