Work

Evaluating Super-Resolution Models in Biomedical Imaging: Applications and Performance in Segmentation and Classification

Year: 2025
Type: article
Abstract: Super-resolution (SR) techniques have gained traction in biomedical imaging for their ability to enhance image quality. However, it remains unclear whether these improvements translate into better performance in clinical tasks. In this study, we provide a comprehensive evaluation of state-of-the-art SR models-including CNN- and Transformer-based architectures-by assessing not only visual quality metrics (PSNR and SSIM) but also their downstream impact on segmentation and classification performance for lung CT scans. Using U-Net and ResNet architectures, we quantify how SR influences diagnostic tasks across different datasets, and we evaluate model generalization in cross-domain settings. Our findings show that advanced SR models such as SwinIR preserve diagnostic features effectively and, when appropriately applied, can enhance or maintain clinical performance even in low-resolution contexts. This work bridges the gap between image quality enhancement and practical clinical utility, providing actionable insights for integrating SR into real-world biomedical imaging workflows.
Language: English
Open Access status: gold
Estimated APC paid: $2,172
OpenAlex ID: W4408996984
FWCI: 3.258
Cites: 27
Cited by: 9
Related to: 10