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Unveiling the PEDOT-polypyrrole hybrid electrode for the electrochemical sensing of dopamine

Year: 2025
Type: article
Abstract: This study presents the electrochemical sensing of dopamine (DA) using an electrode of polypyrrole/poly(3,4-ethylenedioxythiophene) (PEDOT-PPy) thin film. Electrochemical analyses of the PEDOT-PPy thin film for DA sensing were conducted through cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CV analysis demonstrated that PEDOT-PPy exhibited superior electrochemical activity towards DA due to its enhanced conductivity as a high-conducting polymer composite. The DPV results indicated a linear concentration level of 5 nM to 200 µM with a minimal limit of sensing of 5 nM using the PEDOT-PPy electrode material. The fabricated sensor explored the sensitivity of 7.27 µA/µM cm 2 at the 5 to 1000 nM DA concentration and the dopamine diffusion coefficient of 1.3 × 10 –8 cm 2 /s. Additionally, the PEDOT-PPy electrode material displayed excellent reproducibility, selectivity, and stability. Therefore, the PEDOT-PPy composite electrode material shows excellent potential for outperforming other electrode materials in detecting DA.
DOI: 10.1038/s41598-024-82355-1
Authors: Anandhavelu Sanmugam, C. Vanitha, Abdulrahman I. Almansour, K. Karuppasamy, T. Maiyalagan, Hyun-Seok Kim, Dhanasekaran Vikraman, Akram Alfantazi
Institutions: Sri Venkateswara University, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, King Saud University, Khalifa University of Science and Technology, SRM Institute of Science and Technology, Dongguk University
Language: English
Open Access status: gold
Estimated APC paid: $2,690
OpenAlex ID: W4408997012
FWCI: 5.439
Cites: 57
Cited by: 24
Related to: 10