Role of Antimicrobial Air Purifier in Reducing the Microbial Load in the Critical Care Unit in Oncology Center: An Intervention Study
Year: 2025
Type: article
Abstract: Introduction: High quality and effective ventilation system operation plays a major role in maintaining indoor air quality in critical care unit (CCU). Aim of this study was to detect the role of antimicrobial-air-purifier in reducing the colony counts of microbes in air and high surface. Methods: This prospective study was conducted in CCU over a period of 18 months from November 2022 to May 2024 after approval from Hospital Ethics Committee. Microbial load was tested in CCU in the presence of and absence of purifier and air/high touch surface sampling was done by using settle-plate method on consecutive days in two phases (with/without purifier). Microorganism culture and identification was done using VITEK-2, and colony counting was performed using Omeliansky formula. Results: . species [5 (21.74%)]. About 19-23 (85-100%) GNB strains were resistant to third-generation cephalosporins and beta-lactam and beta-lactamase inhibitors. About 9-15 (42.3-67.64%) were resistant to tigecycline and carbapenems. Decreased bloodstream infections/catheter-associated urinary tract infections (CAUTI) rate of 3.49-2.92/3.97-1.95/1,000 patient-days was observed in CCU, while the device utilization ratio was same. Conclusion: Antimicrobial air purifier showed an effective role in decreasing the central line-associated blood stream infections and CAUTI rates in CCU. How to cite this article: Batra VB, Kirtania J, Tiwari S, Kumar P, Kumar A, Chakraborty S. Role of Antimicrobial Air Purifier in Reducing the Microbial Load in the Critical Care Unit in Oncology Center: An Intervention Study. Indian J Crit Care Med 2025;29(4):327-332.
Authors: Amit Kumar, Shashank Tiwari, Vijeta B Batra, Jyotirmay Kirtania, Priyanshu Kumar, Subarna Chakraborty
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408997034