Work

Assessments on the Antibacterial Activity of DL-Valinium Maleate Compound and Z-Scan Analysis

Year: 2025
Type: article
Abstract: DL-valinium maleate [DLVM] compound was grown as single crystals at room temperature by gradual evaporation from an aqueous solution. The classical nucleation theory was examined to maximize the growth conditions for producing high-quality crystals, Nucleation kinetics studies reveal that the crystal has been grown at room temperature 313 K for which predicted critical supersaturation is 6.19. The grown compound DLVM crystallized in a triclinic system with a centrosymmetric space group P1, according to single crystal and powder X-ray diffraction experiments. The lattice parameters were calculated as a= 6.17 Å, b= 9.68 Å, c= 10.59 Å, α= 105.75°, β = 105.67ºand γ = 104.69°with unit cell volume 548.2 Å3. The presence of functional groups in the grown compound has been identified by using Fourier Transform Infrared [FTIR] experiments. NMR studies were used to examine the structural features of DLVM compounds. Since the grown material belongs to the centrosymmetric space group, the material has been found to exhibit third-order NLO property. The Z-scan technique was used to analyse the third-order nonlinear behaviour of the grown crystal. The technique was very useful in evaluating the nonlinear refractive index n2, absorption co-efficient β, and nonlinear optical susceptibility χ(3) of the grown material. Hence, the grown crystal finds useful applications in optoelectronics. The antibacterial activity of the title compound was also studied by using the Agar disc diffusion method against the standard bacteria Klebsiella pneumonia, Staphylococcus aureus and Enterococcus faecalis. The results of the antibacterial activity experiment show that the synthesized DLVM crystal will be a good option for the creation of antibiotic medicines that will combat the tested bacterial strains.
Language: English
Open Access status: hybrid
OpenAlex ID: W4409002927
FWCI:
Cites: 25
Cited by:
Related to: 10