Work

Expression Pattern of TEA Domain Family Member 1 during Orthodontic Tooth Movement and Its Role in Osteoblast Differentiation in Rats

Year: 2025

Type: article

Abstract: Introduction : The Hippo signaling pathway plays a critical role in mediating mechanotransduction ; however, its specific role in orthodontic tooth movement (OTM) remains unclear. Therefore, we investigated the expression patterns of TEA domain family member 1 (TEAD1), a Hippo pathway transcription factor, in rat periodontal tissues during OTM and determined its role in osteoblast differentiation of periodontal ligament (PDL) cells.

Source: THE JOURNAL OF THE STOMATOLOGICAL SOCIETY JAPAN

DOI: 10.5357/koubyou.92.1_60

Authors: LIU Yinan, KOBAYASHI Yukiho, SODSOOK Wasupol, NIKI Yuki, KAMIMOTO Hiroyuki, MORIYAMA Keiji

Institutions: Institute of Science Tokyo, Chulalongkorn University

Language: English

Topic: Orthodontics and Dentofacial Orthopedics

Subfield: Orthodontics

Field: Dentistry

Domain: Health Sciences

Open Access status: diamond

Funder: Japan Society for the Promotion of Science

Awards: Development of a novel therapeutic platform for the treatment of craniosynostosis using exosome-delivered siRNA., Establishment of a Foundation for Novel Orthodontic Treatment Based on Geroscience - Development of Senolytics Application to Oral Science