Work

Simulation and Analysis of an Integrated Cardiopulmonary Gas Exchange Model Under Different Pathological Conditions

Year: 2025

Type: article

Abstract: The development of individualised diagnosis and treatment plans depends on accurate modelling of cardiopulmonary dynamics. A comprehensive cardiopulmonary model that incorporates gas exchange, lung mechanics and cardiovascular interactions has been provided in this work. This model shows high accuracy after being carefully assessed against existing model and clinical observations. The essential physiological parameters are altered to imitate pathological situations such as hypoxia, hypercapnia, chronic obstructive pulmonary disease and pulmonary fibrosis. The findings provide quantitative insights into the progression of the disease by revealing apparent changes in ventilatory response, blood flow dynamics and alveolar gas exchange. These results help practitioners to diagnose diseases in advance.

Source: IEEE Access

DOI: 10.1109/access.2025.3556023

Authors: K. Anjana, Shantanu Saha, N. Selvaganesan

Institution: Indian Institute of Space Science and Technology

Language: English

Topic: Respiratory Support and Mechanisms

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,075