Clinical epidemiology of young men with lower urinary tract symptoms: The SciCOM 3 project
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: A study was performed to determine the most common and most bothersome symptoms and clinical associations in young men (18-40 years) presenting with lower urinary tract symptoms (LUTS). Methods: Cross-sectional study was conducted across 16 centers. Urinary symptoms, impact of bladder problems, bowel symptoms, erectile dysfunction, premature ejaculation, bladder pain, non-bladder myofascial pain, and general well-being were assessed by validated questionnaires. Results: A total of 448 men (median age 30 years) were included. Nocturia ≥1 (89.1%) and feeling of incomplete bladder evacuation (76.6%) were the most common symptoms while the most bothersome symptoms were daytime frequency and nocturia (median score 5; interquartile range 2-8, for both) on the International Consultation on Incontinence Questionnaire for Male LUTS questionnaire. Bladder symptoms were associated with severe or many severe problems (response 5 or 6, on the Patient Perception of Bladder Conditions Questionnaire) in 17.8% of the patients. Men between 18 and 20 years reported greater bother with their bladder condition. Normal erections and "very good" control over ejaculation were reported by 49.8% and 15.6%, respectively. Constipation and loose stools were reported by 22.8% and 12.9%, while bladder pain and non-bladder myofascial pain were reported by 72.5%, and 48.2%, respectively. 17.0% of the patients reported low scores on the WHO-5 Well-Being Scale. Two distinct patient clusters were identified. A larger cluster (63.9%) that presented with voiding symptoms and urgency but fewer sexual or pain symptoms, and a smaller cluster that showed pronounced sexual symptoms, pain, daytime frequency, and nocturia. Conclusions: The most common urinary symptoms in young men are nocturia and a sense of incomplete evacuation. Daytime frequency and nocturia are the most bothersome symptoms. It is important to assess associated symptoms in young men presenting with LUTS.
Source: Indian Journal of Urology
Authors: Sanjay Sinha, Sameer Trivedi, Ankur Mittal, Girdhar Bora, Rishi Nayyar, Pawan Vasudeva, Anita Patel, Harbans Bansal, Vijay Kumar Sarma Madduri, Niraj Kumar, Swarnendu Mandal, Vikas Kumar, Sujith Jose, Girish G Nelivigi, Anil Elhence, Harprit Singh
Institutions: Apollo Hospitals, Institute of Medical Sciences, Banaras Hindu University, All India Institute of Medical Sciences Rishikesh, Post Graduate Institute of Medical Education and Research, All India Institute of Medical Sciences, Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital, Global Hospitals, All India Institute of Medical Sciences Bhubaneswar, Government of Kerala
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409035181