Work

Designing lenalidomide cocrystals with an extended-release profile for improved pulmonary drug delivery

Year: 2025

Type: article

Abstract: This work describes a lenalidomide–melamine cocrystal with a lower solubility than pure lenalidomide, making it suitable for inhalable formulations.

Source: New Journal of Chemistry

DOI: 10.1039/d5nj00425j

Authors: Martin A. Screen, Gary Tomkinson, James F. McCabe, Sean Askin, Clare S. Mahon, Mark R. Wilson, Jonathan W. Steed

Institutions: Durham University, AstraZeneca (United Kingdom)

Language: English

Topic: Crystallography and molecular interactions

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: AstraZeneca, Durham University, Engineering and Physical Sciences Research Council

Award: EPSRC Centre for Doctoral Training in Soft Matter for Formulation and Industrial Innovation (SOFI2)

OpenAlex ID: W4409037620

FWCI: 3.089

Cites: 33

Cited by: 7

Related to: 10