Work

Enantioselective Crystallization on Chiral Hybrid Magnetic Polymeric Particles

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide A new class of Janus chiral magnetic polymeric particles was fabricated for chiral resolution by enantioselective crystallization. N -Acryloyl- l / d -Phe methyl ester beads were prepared with controlled sizes and coated with ferromagnetic permalloy. Chiral discrimination by enantiopure d -Ala crystals was investigated in a model for racemic crystallization. X-ray diffraction and differential scanning calorimetry support the crystallization of the particles. Analysis of optical rotation reveals a d -Ala enantiomeric excess of about 11%, effectively establishing the concept of chiral discrimination by enantioselective crystallization on these Janus chiral magnetic polymeric particles.

Source: ACS Omega

DOI: 10.1021/acsomega.4c11154

Authors: Yarden Ben Moshe, Meir Abuaf, Chen Mordechai, Amos Sharoni, Yitzhak Mastai

Institution: Bar-Ilan University

Language: English

Topic: Crystallization and Solubility Studies

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funder: Israel Science Foundation