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Contrast-Enhanced Ultrasound of a Hepatic Perivascular Epithelioid Cell Tumor: A Case Report and Literature Review

Year: 2025

Type: article

Abstract: Primary hepatic perivascular epithelioid cell tumor (PEComa) is an exceptionally rare mesenchymal neoplasm of borderline malignancy, with limited documentation of its contrast-enhanced ultrasound (CEUS) features in medical literature. In this context, we present a 53-year-old male patient without chronic liver disease, who exhibited a well-circumscribed hypoechoic left hepatic lobe mass on conventional ultrasonography. Subsequent CEUS demonstrated characteristics indicative of malignant tumors, with specific manifestations during the arterial phase, thereby informing clinical decision-making toward surgical resection. Histopathological confirmation of capsular-invasive PEComa underscores the utility of CEUS in characterizing such lesions, particularly in middle-aged patients with incidental solitary hepatic masses lacking predisposing risk factors. These findings advocate for the integration of CEUS into diagnostic algorithms to enhance specificity in atypical hepatic tumor evaluations.

Source: Cureus

DOI: 10.7759/cureus.81579

Authors: Yun-lei Guo, Ying Dang, Hui Zhang, Jie Lian

Institutions: First Affiliated Hospital of Xi'an Jiaotong University, Xi'an Jiaotong University, First Hospital of Xi'an

Language: English

Topic: Tuberous Sclerosis Complex Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409051334