Work

Direct detection of lymphoma cancer cells based on impedimetric immunosensors

Year: 2025

Type: article

Abstract: -hydroxysuccinimide ester) boronic acid (AuNPs@DTSP-BA), followed by the attachment of rituximab monoclonal antibody. Incorporating the boronic acid (BA) component enabled effective oriented immobilization of the antibody, thereby improving the performance of the biosensor. Various spectroscopic techniques were used to characterize the immunosensor. The developed immunosensor demonstrated the ability to detect lymphoma cancer cells across a wide linear range of 100 to 50 000 cells per mL, with a detection sensitivity of 64 cells per mL.

Source: RSC Advances

DOI: 10.1039/d4ra07801b

Authors: Asghar Barani Beiranvand, Fariba Tadayon, Hasan Bagheri

Institutions: Islamic Azad University North Tehran Branch, Baqiyatallah University of Medical Sciences

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042